Program	Introduction
miRNA7	Through the combined detection of 7 microRNA genes, early diagnosis of hepatocellular carcinoma can be realized. Besides that, according to the needs of diagnosis and therapy treatment, multiple testing could be performed to dynamically monitor and compare the comprehensive changes in the expression levels of 7 microRNAs before and after the treatment of hepatocellular carcinoma patients, so as to assist in judging the disease process or treatment effect.
EGFR ALK ROS1	EGFR, a common driver gene in the Asian non-small cell lung cancer (NSCLC) population, is an important biomarker for NSCLC patients treated with targeted drugs such as tyrosine kinase inhibitors (TKIs), including Erizar, Trocor, and Kemena. NSCLC patients with ALK gene fusion and ROS1 gene fusion can benefit from treatment with the targeted drug Phocrizo.
KRAS NRAS PIK3CA BRAF	Mutations in KRAS, NRAS, PIK3CA and BRAF genes are common in many malignant tumors, and the mutation rates in colorectal cancer patients are 20-50%, 1-6%, 10-30%, and 8-15%, respectively. Mutations in these four genes are generally associated with a poorer prognosis, with which colorectal cancer patients become resistant to anti-EGFR antibodies. Some studies suggest that patients with PIK3CA mutations have a higher survival rate when taking aspirin.
Methylation of the SDC2 gene	Compared to normal colorectal tissues, the SDC2 gene shows high levels of methylation in colorectal cancer of different stages and in some intestinal progression adenoma tissues, suggesting that it has clinical value for the detection of colorectal cancer and intestinal progression adenoma.

Program	Introduction
HLA-B27	HLA-B27 can identify the susceptibility of ankylosing spondylitis in a randomized population. For people with a family history of ankylosing spondylitis, HLA-B27 can be used as one of the indicators for the early diagnosis of ankylosing spondylitis. For people with arthritis-like symptoms, HLA-B27 can be used as an important auxiliary tool for clinical diagnosis.
SMN1	Spinal muscular atrophy (SMA) is an autosomal recessive genetic disease, which ranks first among the lethal genetic diseases in children under 2 years of age, and the causative gene is SMN1. Detecting SMN1 in premarital, pre-pregnancy, prenatal, and neonatal stage can effectively prevent birth defects, or help to intervene in a timely manner to improve the morbidity of the patients.

Program	Introduction
CYP2C19	CYP2C19 gene polymorphisms are associated with the efficacy or toxicity of drugs such as clopidogrel and omeprazole.
CYP2C9 VKORC1	CYP2C9 and VKORC1 gene polymorphisms are strongly associated with the clinical efficacy and adverse effects of warfarin oral anticoagulants.
SLCO1B1 APOE	The efficacy and adverse effects of the lipid-lowering drug statin are associated with ApoE and SLCO1B1 gene related loci.
HLA-B5801	The adverse effects of allopurinol, a first-line uric acid-lowering drug for the treatment of gout, are strongly associated with the HLA-B5801 gene.
ALDH2	Testing for polymorphisms in the ALDH2 gene can be used to screen for weak alcohol metabolizers or to guide nitroglycerin dosing.
MTHFR	Folic acid deficiency is a major cause of birth defects and maternal risks such as neural tube malformations, congenital heart disease, cleft lip and palate worldwide. MTHFR is a key enzyme in the folate metabolism pathway, and its genetic mutations can affect the metabolism and absorption of folate.
CYP2D6 CYP2C9 ADRB1 AGTR1 ACE	Mutations in CYP2D6*10, CYP2C9*3, ADRB1 (1165G>C), AGTR1 (1166A>C), and ACE (I/D), can guide the use of three major classes of hypertension medications: β-blockers, angiotensin receptor antagonists, and angiotensin-converting enzyme inhibitors.

Program	Introduction
2019-nCOV	Corona Virus Disease 2019 (COVID-19) is a group of acute respiratory diseases caused by novel coronavirus (2019-nCoV) infection, and nucleic acid testing is an important criterion for its diagnosis.
IFVA IFVB	Influenza viruses include A, B, and C, with type A being the most likely to cause epidemics, followed by type B. Detection of influenza A and B virus RNA in throat swabs can be used for early diagnosis of influenza A and B, and to assist in rational clinical treatment. Meanwhile, it can be used for epidemiological monitoring and analysis to control the wide spread of influenza virus.
MP	Mycoplasma pneumoniae (MP) is an intermediate microorganism between bacteria and viruses that usually causes mild upper respiratory tract infections such as sore throat, laryngitis, and bronchitis, but in severe cases it can also lead to pneumonia, which accounts for up to 50% of non-bacterial pneumonia.
CP	Chlamydia pneumoniae (CP) infection is an infectious disease caused by Chlamydia pneumoniae, which mainly causes atypical pneumonia in adults and adolescents, and acute respiratory infections such as bronchitis, pharyngitis and tonsillitis.
TB	Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis (TB) infection, and China ranks the third high burden of tuberculosis worldwide. The in vitro qualitative detection of TB nucleic acids in human sputum samples can assist in the detection of latent TB infections and identify tuberculosis patients as early as possible, as well as the assessment of the efficacy of medication, and at the same time, it can be used for tuberculosis epidemiological monitoring and analysis.
RSV	Respiratory syncytial virus (RSV), a single-stranded negative-stranded RNA virus belonging to the genus Pneumovirus in the family Paramyxoviridae, is the most common viral pathogen of acute lower respiratory tract infections in infants and young children, with a high risk especially in children under 2 years of age, and is strongly associated with wheezing episodes and asthma thereafter

Program	Introduction
CA6 CA10	Coxsackievirus A6 (CA6) and coxsackievirus A10 (CA10) are important pathogens causing hand, foot, and mouth disease, and the proportion of infections among patients with hand, foot, and mouth has gradually increased in recent years,
CA16 EV71	Hand, foot and mouth disease (HFMD) is an acute infectious disease in children caused by a large group of enteroviruses, and severe cases and deaths mainly associated with enterovirus 71 (EV71), coxsackievirus A16 (CA16).
EB	Epstein-Barr virus (EBV) infection causes infectious mononucleosis, African childhood lymphoma, and nasopharyngeal carcinoma. EBV testing is included in nasopharyngeal carcinoma guidelines to aid in diagnosis or prognosis.
MV	Measles is an acute infectious disease caused by the measles virus (MV), which is highly contagious and most commonly seen in children.

Program	Introduction
TOX	Toxoplasma gondii is an intracellular parasite, also known as trichinella. It is parasitic in cells and travels with the bloodstream to all parts of the body, destroying the brain, heart, and fundus of the eye, resulting in a decrease in immunity and a variety of diseases. The main way of transmission is to ingest food contaminated by body fluids or feces of feline and canine animals. In pregnant women, toxoplasmosis can be transmitted to the fetus through the placenta, and in a small number of cases, stillbirth deformities and mental retardation can develop. Adults infected with toxoplasmosis have symptoms similar to the flu and gastroenteritis. Acute toxoplasmosis can lead to inflammation of various organs and death
RV	Rubella is an acute respiratory infectious disease caused by rubella virus (RV) infection, and the susceptible age is 1-5 years old preschool children.
CMV	Human cytomegalovirus (HCMV) is an important pathogen for eugenics testing, and when pregnant women are infected, it may be transmitted to the fetus, potentially causing fetal liver damage, as well as hearing, eye disease, dental disease and other sequelae, especially on the nervous system is more damaging
HSV	Herpes simplex virus type II (HSV-II) mainly causes genital infections below the waist and is transmitted through sexual contact
GBS	Group B Streptococcus (GBS) is one of the most important causative pathogens of perinatal infections in mothers and infants. When pregnant women are infected, there is a 50% probability of transmission to the fetus or newborn if without intervention, which may lead to a series of serious illnesses such as neonatal pneumonia, meningitis, sepsis, and so on.

Program	Introduction
CT	Chlamydia trachomatis (CT) is an important causative pathogen of sexually transmitted diseases (STDs), which can cause infertility.
NG	Neisseria gonorrhoeae, NG tends to invade the mucosa of the urethra, often located in neutrophils. It causes purulent inflammatory diseases of the genitourinary system and is one of the most common sexually transmitted infections.
UU	Ureaplasma urealyticum (UU) is the main pathogen causing non-gonococcal urethritis (NGU), mucous cervicitis, endometritis, acute salpingitis and infertility in both male and female, and it is mainly transmitted by sexual contact.
MG	Mycoplasma genitalium (MG) is one of the important pathogens of the human genitourinary tract. Several studies have shown that Mg infection is associated with symptomatic NGU (non-gonococcal urethritis), prostatitis, epididymitis, cervicitis, endometritis, pelvic inflammatory disease, infertility and spontaneous abortion, neonatal respiratory tract infection, and even the progression of Human Immunodeficiency Virus (HIV) infected patients to AIDS (AIDS).
MH	Mycoplasma hominis (Mh) is a common pathogen parasitizing the human urinary tract and genitals, which can cause urinary tract infections and genital inflammation. It is closely associated with spontaneous abortion, puerperal fever, endometriosis, and tubal infections, as well as infertility.
HPV	Human papillomavirus (HPV) is a common virus that primarily spreads through sexual contact and is known for its affinity to epithelial cells. Persistent infection with high-risk HPV is considered a significant factor contributing to cervical cancer.
HIV	AIDS is a significant infectious disease that poses a threat to human health. Nucleic acid testing plays a crucial role in the diagnosis and treatment of AIDS, as it can detect the infection 7-10 days post-exposure, effectively reducing the window period. In the follow-up treatment and monitoring, it provides comprehensive scientific surveillance of the entire AIDS course, aiding in the early detection of virological failures, enabling timely adjustments to the treatment plan, and mitigating the risk of accumulating drug resistance. Ultimately, this contributes to improving the long-term survival rates of patients.

Program	Introduction
HAV	Hepatitis A virus is a single-stranded DNA virus. This virus is very resistant to heat, acid and alkali and is the most important pathogen causing acute hepatitis in the world. Typically, transmission occurs through contact pathways.
HBV	Hepatitis B virus replication levels and genotypes are strongly associated with disease progression, clinical manifestations after infection, prognosis and response to antiviral therapy.
HCV	The incidence of viral hepatitis in China exceeds one million cases per year, with hepatitis B and C being the predominant types.
HDV	Hepatitis D is a defective virus that relies on the assistance of hepatitis B virus (HBV) for replication. Its transmission primarily occurs through blood transfusion or the use of blood products, and it can also spread through close contact, including vertical transmission from mother to child. Hepatitis D is an infection based on infection with hepatitis B. It is a double infection, which can easily lead to severe hepatitis, chronic hepatitis, cirrhosis and even primary liver cancer
HEV	Hepatitis E is a major form of hepatitis in today's developing countries, posing a serious threat to human health. In recent years, its incidence has been rapidly increasing.
HGV	Hepatitis G Virus is a single positive-stranded RNA virus. It is mainly transmitted by blood transfusion and other non-intestinal routes, and mother-to-child transmission and medical transmission also exist. Hepatitis G virus can cause acute hepatitis or chronic hepatitis; it can be infected simultaneously or sequentially with hepatitis A and E viruses, and more commonly with hepatitis B and C viruses.
TTV	Transfusion-transmitted viral hepatitis (TTV) is a single-stranded DNA virus, primarily transmitted through bloodborne routes. TTV is a new DNA virus. It is associated with the development of cirrhosis of unknown origin and fulminant liver failure. It has a high prevalence in patients with chronic hepatitis C and chronic hepatitis B, and has the potential to become hepatitis VIII.